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 - Sad rainy day

Seasonal Affective Disorder (SAD) appears to be brought on in the darker months of the year due to a drop in serotonin, which is mediated by the serotonin transporter protein (SERT), according to a longitudinal PET study presented Monday in Berlin during the Congress of the European College of Neuropsychopharmacology.

 - liver

Challenging imaging artifacts in image guidance for interventional liver procedures such as those caused by biopsy needle could be ameliorated with an optical imaging technique called epifluorescence imaging, according to a study published Oct. 10 ahead of print in Radiology.

 - red light, stop

Due to manufacturing delays and shortage in supply, Ra-223, aka Xofigo, is currently not available, the FDA announced Oct. 7. Neither the FDA nor the drug’s maker, Bayer Healthcare, have released an estimated date for when supply of Ra-223 will be restored.

 - Neon Heart

A new method of image reconstruction that synchronizes a preset phase of respiration using electrocardiography (ECG) and bioimpedance raises the image quality of PET usually degraded by breathing artifacts, the University of Eastern Finland (UEF) announced Oct. 10.

 - Neurons

A comprehensive 3D model of human neuronal pathophysiology leading to Alzheimer’s disease is now complete. The final model provides confirmation of how amyloid plaque build-up and tau neurofibrillary tangles are not just related to onset of disease, but that amyloid hastens tau pathology, according to a letter published online Oct. 12 in Nature.