The Living Lab Structural Biology Center was formed through a cooperative research and development agreement between the National Institutes of Health (NIH), in Bethesda, Md., and FEI, in Hillsboro, Ore., a scientific instruments company, to help accelerate medical discoveries relating to global health challenges, such as cancer and HIV/AIDS. The lab will utilize near-atomic resolution microscopy and other structural biology technologies.
The Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium has released biomarker data from studies intended to improve the ability to diagnose and measure the progression of Alzheimer’s disease.
Researchers at the University of Washington School of Medicine in Seattle have received a $7 million five-year renewal grant award from the National Institutes of Health (NIH)/National Cancer Institute (NCI) to continue research in molecular imaging of cancer and its response to therapy. This new award is funded through 2016.
A new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of disease and ultimately enhance diagnosis and treatment, according to a new report from the National Research Council.
Researchers at Lawrence Livermore National Laboratory in Livermore, Calif., recently received $3 million from the National Institutes of Health to acquire a new biomedical accelerator mass spectrometry instrument. The instrument will provide analysis for medical and other biological research.
The National Institutes of Health (NIH) Clinical Center has begun imaging patients on a whole-body simultaneous PET and MRI device (Siemens Healthcare, Biograph mMR) as a new weapon in its arsenal to diagnose and treat traumatic brain injury and post-traumatic stress disorder among military service members and civilians.
The Society of Nuclear Medicine (SNM) has announced the recipients of the 2011-2013 SNM Wagner-Torizuka Fellowship, which is a two-year fellowship designed to provide extensive training and experience in the fields of nuclear medicine and molecular imaging for Japanese physicians in the early stages of their careers.
Researchers successfully fused real-time ultrasound to coregistered CT and FDG PET studies and combined the datasets with electromagnetic device tracking to perform percutaneous and intraoperative biopsies and radiofrequency ablation, according to a study published in the September issue of Radiology.
Written by James Brice
SPECT and PET-based strategies have started to refine diagnosis and treatment planning for Parkinson’s disease and epilepsy.
Researchers at the Biodesign Institute at Arizona State University have found a way to get molecular binding agents to act like antibodies and, in the process, optimize the binding agents’ affinity for targeted proteins. The development revealed important nuances of protein function and could lead to better diagnosis and treatment for a range of diseases. The researchers published their findings Aug. 16 in the journal ChemBioChem.
Methodist Hospital Research Institute (MHRI) in Houston is partnering with Philips Healthcare to build a multi-modality suite capable of imaging highly infectious patients in a contained, quarantine-like environment.
Researchers are reporting promising results for earlier diagnosis of liver cancer. In lab tests, the team used gold nanoparticles ringed by a charged polymer coating and an x-ray scatter imaging technique to spot tumor-like masses as small as 5 mm. The approach, published June 6 in Nano Letters, is reportedly the first time that metal nanoparticles have been used as agents to enhance x-ray scattering signals to image tumor-like masses.
The RSNA Research and Education Foundation will fund 74 grants totaling nearly $2.7 million in 2011, the largest amount ever granted by the foundation in a single year.
The National Institutes of Health (NIH) have awarded researchers from Rensselaer Polytechnic Institute in Troy, N.Y., a $1.2 million grant to develop software and patient-specific virtual phantoms to calculate and track patient radiation exposure from CT imaging.
For the first time in 27 years, the Alzheimer’s Association and the National Institute on Aging (NIA) have published new criteria for the diagnosis of Alzheimer’s disease, offering a general framework for early diagnosis but considering existing research unripe for definitive pre-clinical criteria.
Researchers have demonstrated that a process using nanotechnology combined with mass spectrometric analysis can assess whether cancer drugs hit their targets, which may help reduce drug side effects, according to a study published online March 31 in Agnewandte Chemie International Edition.
Written by Manjula Puthenedam, PhD, & Mary C. Tierney, MS
FDG-PET is highly accurate in diagnosing progressive neurodegenerative disease such as Alzheimer’s disease (AD) even if cognitive dysfunction is only mild. Thus, novel brain imaging probes targeting, for instance, beta-amyloid will likely serve a different purpose. They will play an important role if beta-amyloid is confirmed as a molecular target of effective therapy, and drugs that target beta-amyloid are actually developed.
Presenting last week at a National Institutes of Health (NIH) summit on managing CT radiation dose in Bethesda, Md., representatives from the American College of Radiology (ACR) discussed initiatives for minimizing CT radiation dose ranging from technology and education to public policy and voluntary reporting.
Nanotechnology may open a new opportunity for the treatment of liver cancer, according to researchers from Penn State College of Medicine in Hershey, Penn., who used molecular-sized bubbles filled with chemotherapy drugs to prevent cell growth and initiate cell death in test tubes and mice.
A large proportion of physicians do not participate in clinical cancer trials, with a lack of funding and underdeveloped hospital infrastructures and IT preventing nearly half of cancer specialists from enrolling patients in research trials, according to a study published Feb. 11 in the Journal of the National Cancer Institute.
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