18F-flutemetamol PET imaging demonstrates strong concordance with histopathology irrespective of timing and sequence of exams in prospective and retrospective settings, and shows promise as a valuable tool to study and possibly facilitate diagnosis of Alzheimer’s disease, both in patients with suspected normal pressure hydrocephalus, and among the wider population, according to a pooled analysis of four studies presented at the 2012 Human Amyloid Imaging (HAI) conference in Miami, Fla.