The radiopharmaceutical, I-131-MIP-1466, which is designed to deliver a therapeutic dose of radiation to metastatic prostate cancer, will enter a clinical trial to evaluate its efficacy and benefits for patients.

With the exception of liver metastases, whole-body imaging of estrogen receptor (ER) expression with 18F-FES, an ER-specific PET tracer, can be a valuable additional diagnostic tool when standard work-up is inconclusive, particularly in breast cancer patients, according to a study published in the February issue of the Journal of Nuclear Medicine.

The malignancy rate for MR-detected breast masses less than or equal to 5 mm has been shown to be greater than 20 percent, indicating that these small masses should be viewed with a high degree of suspicion when seen in staging breast MRI exams, according to a study published in the January issue of Academic Radiology.

Inflammation, as assessed by 18F-FDG-PET uptake and histology, is increased in plaques containing high-risk morphological (HRM) features and rises with increasing number of HRM, according to a study in the January issue of Circulation: Cardiovascular Imaging. Study authors suggested that data support the concept that inflammation accumulates relative to the burden of morphological abnormalities.

A new magnetic resonance spectroscopy (MRS) technique may offer a method to detect and track a protein associated with a genetic mutation in brain tumor cancer cells. The method could inform diagnosis of glioma and provide prognostic information, according to a study published online Jan. 26 in Nature Medicine.

Often healthcare services in the U.S. are overutilized, which can lead to high healthcare spending. Expanding guidelines and establishing appropriate use criteria for more healthcare services could help eliminate this overuse and in turn reduce high healthcare spending, according to an editorial published in the Jan. 24 issue of the Archives of Internal Medicine.

18F-flutemetamol PET imaging demonstrates strong concordance with histopathology irrespective of timing and sequence of exams in prospective and retrospective settings, and shows promise as a valuable tool to study and possibly facilitate diagnosis of Alzheimer’s disease, both in patients with suspected normal pressure hydrocephalus, and among the wider population, according to a pooled analysis of four studies presented at the 2012 Human Amyloid Imaging (HAI) conference in Miami, Fla.

An interim 18F-FDG PET/CT exam after two cycles of neoadjuvant chemotherapy was predictive of pathologic response and disease-free survival in patients with triple-negative breast cancer, an aggressive subtype of breast cancer, according to a prospective study published online Jan. 12 in the Journal of Nuclear Medicine.

The team at Johns Hopkins In-Vivo Cellular and Molecular Imaging Center in Baltimore is using novel imaging tools to discover new early detection methods for cancers existing in cells, and study its prevention and elimination before spreading to other organs and tissues.

Different ingredients in marijuana appear to affect regions of the brain differently during brain processing functions involving responses to certain visual stimuli and tasks, according to a study published in the January issue of Archives of General Psychiatry.

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FDG PET could be used as a noninvasive surrogate marker for tumor growth and viability in treatment of head and neck cancer, based on a rodent model study published in the December issue of Radiology.

FDG uptake of thymus measured by PET/CT is an effective indicator for the differentiation of mediastinal lymphoma from normal thymus in pediatric patients, according to a study published online Dec. 12 in Radiology.

In an era of inexpensive statins, treating all Americans in the U.S. who are at intermediate risk of coronary heart disease (CHD) with statins (men and women) and aspirin (men only) is effective and less expensive than stress testing and treating only those patients with a positive result, according to a simulation study published online Dec. 5 of Circulation.

Women diagnosed with breast cancer are increasingly burdened by multiple imaging appointments prior to surgery, according to researchers from Fox Chase Cancer Center in Philadelphia, who presented the findings Dec. 9 at the San Antonio Breast Cancer Symposium.

Medicare beneficiaries who underwent coronary computed tomography angiography (CCTA) in a nonacute setting were more likely to undergo subsequent invasive cardiac procedures and have higher coronary artery disease spending than patients who underwent stress testing, according to a study published in the Nov. 16 issue of the Journal of the American Medical Association.

In a performance evaluation, the National Electrical Manufacturers Association found the NanoPET/CT system to be of significant value in preclinical research, according to an article published in the November issue of the Journal of Nuclear Medicine.

In an effort to speed the development of cancer treatments that target the genetic weaknesses in each individual patient’s tumor, Dana-Farber Cancer Institute and Brigham and Women’s Hospital have launched Profile, a program to scan tumor tissue from adult cancer patients for hundreds of gene mutations linked to cancer.

The complication rates in treating benign thyroid nodules with radiofrequency (RF) ablation are low, though various complications may still occur, warranting preventive measures, according to a study published in the October issue of Radiology.

The results of three studies, released Oct. 21 during a meeting of the North Central Section of the American Urological Association, validated previous research that suggested C-11 choline PET/CT scans can be utilized as a staging and potentially therapeutic tool in prostate cancer.

Boston University School of Medicine has received a $13.6 million grant to be the lead institution in a study aimed at developing technologies for the early detection of lung cancer. The five-year multi-site, multi-phase study that will focus on active military personnel and veterans is funded by the U. S. Department of Defense Lung Cancer Research Program.