Individuals with deterministic genes in whom it is known that Alzheimer’s disease (AD) will develop appear to show differences in beta-amyloid distribution when compared with non-dominantly inherited AD patients, helping to consolidate evidence that PET and MRI can depict brain changes well before the arrival of AD-related symptoms, according to preliminary findings presented July 20 at the 2011 Alzheimer’s Association International Conference in Paris.
Roswell Park Cancer Institute in Buffalo, N.Y., has been named a Center of Quantitative Imaging Excellence by the National Cancer Institute (NCI).
Known to be significantly more susceptible to dementia, individuals with Down syndrome appear to display age-related increases in amyloid senile plaques and tau neurofibrillary tangles that mirror those increases in Alzheimer’s patients as viewed with PET, according to a study published in the June issue of Archives of Neurology.
The automated measurement of temporoparietal brain region volumes is a highly accurate predictor of memory loss in healthy elderly persons, indicating that these underlying characteristics could help clinicians identify likely cases of pre-clinical Alzheimer’s and enable them eventually to prevent the disease’s progression, according to an article published in the June issue of
Radiology.
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