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 - Robert W. Atcher, PhD, MBA

I have been struggling recently with the notion that genomics is going to revolutionize our ability to diagnose and treat disease. Why? A basic tenet of information theory is simple: the more precisely you can measure something, the less information it contains.

 - Sentinel lymph

Intraoperative lymphatic mapping provides surgeons, oncologists and referring physicians with vital information about potential malignancy in the lymphatic system, especially that of sentinel lymph nodes—usually the first check point for the diasporas of metastatic cancer cells that drain from primary tumors. Patients have a better chance of avoiding the increased morbidity associated with extensive nodal dissection by undergoing a biopsy of the sentinel lymph nodes most likely to contain metastatic disease.

 - older man

As men with localized prostate cancer weigh the multitude of treatment options, they may want to consider the interplay between comorbid conditions, age and tumor features with other-cause mortality and disease-specific mortality. Older men with several comorbid conditions face a higher risk of other-cause mortality within 10 years of diagnosis, according to a study published May 20 in Annals of Internal Medicine.

 - Andrei Iagaru, MD

Prostate cancer patients with advanced tumors that have spread to bone have a poor prognosis; men with castrate-resistant prostate cancer generally live three to five years after diagnosis.

 - Parkinson-Structural MR

The days of the clinical exam leading the way in evaluating Parkinson’s disease are on the way out. A better understanding of how to use imaging has led to advances in diagnosing and monitoring the condition, and may hold the key to evaluating effective treatment.