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First-order treatment of cancer typically involves chemo and/or radiation therapy and surgical intervention, but radionuclide therapies offer some advantages for select patients by delivering a very intense dose sequestered to affected tumor sites. These are the therapies currently available and in clinical trials, with a few novel compounds waiting for validation in the wings.
There is a wide variety of radionuclide therapies available for oncologic use and for benign disease such as overactive thyroid or as a radiation synovectomy for arthritis. Radionuclide therapies are fashioned into targeted treatments by either localized injection, by minimally invasive radioembolization and, in the case of radioimmunotherapy, by labeling the radionuclide with antibodies that zero in on...