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By: Kathy F. Mahdoubi

First-order treatment of cancer typically involves chemo and/or radiation therapy and surgical intervention, but radionuclide therapies offer some advantages for select patients by delivering a very intense dose sequestered to affected tumor sites. These are the therapies currently available and in clinical trials, with a few novel compounds waiting for validation in the wings.

There is a wide variety of radionuclide therapies available for oncologic use and for benign disease such as overactive thyroid or as a radiation synovectomy for arthritis. Radionuclide therapies are fashioned into targeted treatments by either localized injection, by minimally invasive radioembolization and, in the case of radioimmunotherapy, by labeling the radionuclide with antibodies that zero in on...

 - Robert W. Atcher, PhD, MBA
By: Robert W. Atcher, PhD, MBA
During the past five years, I have spent a considerable amount of time on the issue of supply of Tc-99m and its parent, Mo-99.
 - Markers
By: Candace Stuart
Two is better than one. At least that may prove to be the case with hybrid approaches that combine PET’s ability to assess myocardial blood flow with other modalities for diagnosing coronary artery...
 - Doctor with brain
By: Kathy F. Mahdoubi
Molecular imaging of psychiatric disorders has taken a few turns around the lab as a concept, and while some potential imaging methods, namely dopamine transport scanning, have shown some potential,...
 - Laura S. Sasportas, PhD
By: Kathy F. Mahdoubi
There are a number of perennial destinations for the molecular imaging set that deliver cutting-edge research and promote clinical discussion, but, for many clinicians and researchers, the Society of...
 - RF Heating
By: Anna Steere
While MRI is often considered one of the safer imaging modalities due to its lack of ionizing radiation, other dangers remain for patients, with thermal burns being a chief concern. 
 - Barry A. Siegel, MD
By: Kathy F. Mahdoubi
As the 2014 Annual Meeting for the Society of Nuclear Medicine and Molecular Imaging (SNMMI) came to a close this year in St. Louis, Molecular Imaging Insight sat down with Barry A. Siegel, MD,...
 - Hyperpolarized MR
By: Kathy F. Mahdoubi
Hyperpolarized MRI, also known as hyperpolarized MRSI (or HP-MRSI), is a new technique representing a major development in molecular MR currently making the rounds in the international molecular...
 - Labyrinth
By: Dave Pearson
The challenge was delivered with stark clarity. “We need to establish a new approach to make it easy and affordable for our faculty to quickly transition their imaging probe research from cells and...
 - boxing gloves
By: Claudette Lew
Advanced low-grade non-Hodgkin lymphoma (NHL) typically leads to relapse and death in patients who undergo conventional chemo and radiation therapies, but the emergence of radioimmunotherapy (RIT) in...
 - Alzheimer's
By: Kathy F. Mahdoubi
A number of factors are standing out as promoters for and protectors against the development of Alzheimer’s disease, according to research presented during the 2014 Alzheimer’s Association...